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Population Pharmacokinetics of Necitumumab in Cancer Patients
Necitumumab is a second-generation, recombinant, human immunoglobulin G1, epidermal growth factor (EGFR) receptor antibody that specifically blocks the ligand binding site of EGFR. Necitumumab potentially acts by blocking ligand epidermal growth factor (EGF) binding-mediated activation of the EGFR s...
Autores principales: | Long, Amanda, Chigutsa, Emmanuel, Wallin, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385201/ https://www.ncbi.nlm.nih.gov/pubmed/27696220 http://dx.doi.org/10.1007/s40262-016-0452-x |
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