Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice

The protein kinase B (PKB/Akt), found in three distinctive isoforms (PKBα/Akt1, PKBβ/Akt2, PKBγ/Akt3), is implicated in a variety of cellular processes such as cell development, growth and survival. Although Akt3 is the most expressed isoform in the brain, its role in cerebral functions is still unc...

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Detalles Bibliográficos
Autores principales: Bergeron, Yan, Bureau, Geneviève, Laurier-Laurin, Marie-Élaine, Asselin, Eric, Massicotte, Guy, Cyr, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385361/
https://www.ncbi.nlm.nih.gov/pubmed/28442992
http://dx.doi.org/10.3389/fnmol.2017.00102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385361/
https://www.ncbi.nlm.nih.gov/pubmed/28442992
http://dx.doi.org/10.3389/fnmol.2017.00102

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