Cargando…

Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

AIM: To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil (5-FU)-induced diarrhea. METHODS: Diarrhea was induced in wild-type (WT), Fn14 knockout (KO), and IL-13 receptor (IL-13R)α1 KO BALB/c mice using a single injection of 5-FU. Histological analysis, cytokine analysis, and flow c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sezaki, Takuhito, Hirata, Yuki, Hagiwara, Teruki, Kawamura, Yuki I, Okamura, Tadashi, Takanashi, Rieko, Nakano, Kenta, Tamura-Nakano, Miwa, Burkly, Linda C, Dohi, Taeko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385396/ https://www.ncbi.nlm.nih.gov/pubmed/28428709 http://dx.doi.org/10.3748/wjg.v23.i13.2294

Ejemplares similares

Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma
por: Otsubo, Takeshi, et al.
Publicado: (2015)

The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson’s disease
por: Mustafa, S., et al.
Publicado: (2016)

TWEAK and Fn14 in the Neurovascular Unit
por: Yepes, Manuel
Publicado: (2013)

TWEAK/Fn14 Signaling Is Required for Liver Regeneration after Partial Hepatectomy in Mice
por: Karaca, Gamze, et al.
Publicado: (2014)

Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and Other TNF/TNFR Superfamily Members That Activate Non-Canonical NFκB Signaling
por: Burkly, Linda C.
Publicado: (2015)

Retrotransposition of Long Interspersed Nucleotide Element-1 Is Associated with Colitis but Not Tumors in a Murine Colitic Cancer Model
por: Otsubo, Takeshi, et al.
Publicado: (2015)

TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus
por: Doerner, Jessica, et al.
Publicado: (2015)

TWEAK/Fn14 Activation Participates in Skin Inflammation
por: Liu, Qilu, et al.
Publicado: (2017)

A Bioinformatics Resource for TWEAK-Fn14 Signaling Pathway
por: Bhattacharjee, Mitali, et al.
Publicado: (2012)

Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma
por: Shiba, Daiki, et al.
Publicado: (2018)

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation
por: Wilhelm, Annika, et al.
Publicado: (2016)

Neuropsychiatric Lupus, the Blood Brain Barrier, and the TWEAK/Fn14 Pathway
por: Stock, Ariel D., et al.
Publicado: (2013)

TWEAK/Fn14 system and crescent formation in IgA nephropathy
por: Sasaki, Yohei, et al.
Publicado: (2015)

The TWEAK/Fn14/CD163 axis—implications for metabolic disease
por: Ratajczak, Wiktoria, et al.
Publicado: (2021)

TWEAK/Fn14 Signalling Regulates the Tissue Microenvironment in Chronic Pancreatitis
por: Abu Bakar, N. Dianah B., et al.
Publicado: (2023)

Novel murine model of congenital diabetes: The insulin hyposecretion mouse
por: Nakano, Kenta, et al.
Publicado: (2018)

TWEAK/Fn14 Axis: A Promising Target for the Treatment of Cardiovascular Diseases
por: Blanco-Colio, Luis M.
Publicado: (2014)

Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice
por: Meijboom, Katharina E., et al.
Publicado: (2022)

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis
por: Dharmapatni, Anak ASSK, et al.
Publicado: (2011)

The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting
por: Bhatnagar, S, et al.
Publicado: (2012)

TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney Disease
por: Poveda, Jonay, et al.
Publicado: (2013)

TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic
por: Cheng, Emily, et al.
Publicado: (2013)

TWEAK/Fn14 Signaling Axis Mediates Skeletal Muscle Atrophy and Metabolic Dysfunction
por: Sato, Shuichi, et al.
Publicado: (2014)

Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism (†)
por: Aido, Ahmed, et al.
Publicado: (2021)

The TWEAK Receptor Fn14 is a Novel Therapeutic Target in Melanoma: Immunotoxins Targeting Fn14 Receptor for Malignant Melanoma Treatment
por: Zhou, Hong, et al.
Publicado: (2012)

TWEAK-Independent Fn14 Self-Association and NF-κB Activation Is Mediated by the C-Terminal Region of the Fn14 Cytoplasmic Domain
por: Brown, Sharron A. N., et al.
Publicado: (2013)

TWEAK/Fn14 Activation Participates in Ro52-Mediated Photosensitization in Cutaneous Lupus Erythematosus
por: Liu, Yale, et al.
Publicado: (2017)

Activation of TWEAK/Fn14 signaling suppresses TRAFs/NF-?B pathway in the pathogenesis of cancer
por: Gupta, Gaurav, et al.
Publicado: (2021)

Genetic locus responsible for diabetic phenotype in the insulin hyposecretion (ihs) mouse
por: Nakano, Kenta, et al.
Publicado: (2020)

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice
por: Mittal, Ashwani, et al.
Publicado: (2010)

TWEAK-Fn14 Cytokine-Receptor Axis: A New Player of Myocardial Remodeling and Cardiac Failure
por: Novoyatleva, Tatyana, et al.
Publicado: (2014)

A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis
por: Méndez-Barbero, Nerea, et al.
Publicado: (2019)

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells
por: Roos, Alison, et al.
Publicado: (2017)

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity
por: Güner, Gökhan, et al.
Publicado: (2022)

Fn14-Fc suppresses germinal center formation and pathogenic B cells in a lupus mouse model via inhibition of the TWEAK/Fn14 Pathway
por: Min, Hong-Ki, et al.
Publicado: (2016)

A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats
por: Shimizu, Yukiko, et al.
Publicado: (2018)

TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
por: Sidler, Daniel, et al.
Publicado: (2017)

TWEAK-Fn14 Axis Induces Calcium-Associated Autophagy and Cell Death To Control Mycobacterial Survival in Macrophages
por: Chen, Yi-Ming, et al.
Publicado: (2022)

Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing
por: MARUSUGI, Kiyoma, et al.
Publicado: (2016)

TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier
por: Stephan, Delphine, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0n9vo5452rjhrj52284dj7hf64