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Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

AIM: To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil (5-FU)-induced diarrhea. METHODS: Diarrhea was induced in wild-type (WT), Fn14 knockout (KO), and IL-13 receptor (IL-13R)α1 KO BALB/c mice using a single injection of 5-FU. Histological analysis, cytokine analysis, and flow c...

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Detalles Bibliográficos
Autores principales:	Sezaki, Takuhito, Hirata, Yuki, Hagiwara, Teruki, Kawamura, Yuki I, Okamura, Tadashi, Takanashi, Rieko, Nakano, Kenta, Tamura-Nakano, Miwa, Burkly, Linda C, Dohi, Taeko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385396/ https://www.ncbi.nlm.nih.gov/pubmed/28428709 http://dx.doi.org/10.3748/wjg.v23.i13.2294

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