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VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells

During metastasis, breakdown of the endothelial barrier is critical for tumor cell extravasation through blood vessel walls and is mediated by a combination of tumor secreted soluble factors and receptor-ligand interactions. However, a complete mechanism governing tumor cell transendothelial migrati...

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Detalles Bibliográficos
Autores principales: Aragon-Sanabria, Virginia, Pohler, Steven E., Eswar, Vikram J., Bierowski, Matthew, Gomez, Esther W., Dong, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385522/
https://www.ncbi.nlm.nih.gov/pubmed/28393886
http://dx.doi.org/10.1038/srep45835

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