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VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells
During metastasis, breakdown of the endothelial barrier is critical for tumor cell extravasation through blood vessel walls and is mediated by a combination of tumor secreted soluble factors and receptor-ligand interactions. However, a complete mechanism governing tumor cell transendothelial migrati...
Autores principales: | Aragon-Sanabria, Virginia, Pohler, Steven E., Eswar, Vikram J., Bierowski, Matthew, Gomez, Esther W., Dong, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385522/ https://www.ncbi.nlm.nih.gov/pubmed/28393886 http://dx.doi.org/10.1038/srep45835 |
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