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Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells

The Polycomb repressive complex 1 (PRC1) is essential for fate decisions of embryonic stem (ES) cells. Emerging evidence suggests that six major variants of PRC1 complex, defined by the mutually exclusive presence of Pcgf subunit, regulate distinct biological processes, yet very little is known abou...

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Detalles Bibliográficos
Autores principales: Yan, Yun, Zhao, Wukui, Huang, Yikai, Tong, Huan, Xia, Yin, Jiang, Qing, Qin, Jinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385539/
https://www.ncbi.nlm.nih.gov/pubmed/28393894
http://dx.doi.org/10.1038/srep46276

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