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Metastasis-associated protein 1 is an upstream regulator of DNMT3a and stimulator of insulin-growth factor binding protein-3 in breast cancer

Despite a recognized role of DNA methyltransferase 3a (DNMT3a) in human cancer, the nature of its upstream regulator(s) and relationship with the master chromatin remodeling factor MTA1, continues to be poorly understood. Here, we found an inverse relationship between the levels of MTA1 and DNMT3a i...

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Detalles Bibliográficos
Autores principales: Deivendran, S., Marzook, Hezlin, Santhoshkumar, T. R., Kumar, Rakesh, Pillai, M. Radhakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385551/
https://www.ncbi.nlm.nih.gov/pubmed/28393842
http://dx.doi.org/10.1038/srep44225