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Quercetin Inhibits Pulmonary Arterial Endothelial Cell Transdifferentiation Possibly by Akt and Erk1/2 Pathways
This study aimed to investigate the effects and mechanisms of quercetin on pulmonary arterial endothelial cell (PAEC) transdifferentiation into smooth muscle-like cells. TGF-β1-induced PAEC transdifferentiation models were applied to evaluate the pharmacological actions of quercetin. PAEC proliferat...
Autores principales: | Huang, Shian, Zhu, Xiulong, Huang, Wenjun, He, Yuan, Pang, Lingpin, Lan, Xiaozhong, Shui, Xiaorong, Chen, Yanfang, Chen, Can, Lei, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385898/ https://www.ncbi.nlm.nih.gov/pubmed/28428963 http://dx.doi.org/10.1155/2017/6147294 |
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