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Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

Many eukaryotic cells regulate their mobility by external cues. Genetic studies have identified >100 components that participate in chemotaxis, which hinders the identification of the conceptual framework of how cells sense and respond to shallow chemical gradients. The activation of Ras occurs d...

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Detalles Bibliográficos
Autores principales: van Haastert, Peter J. M., Keizer-Gunnink, Ineke, Kortholt, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385941/
https://www.ncbi.nlm.nih.gov/pubmed/28148648
http://dx.doi.org/10.1091/mbc.E16-10-0733

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