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Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement
Many eukaryotic cells regulate their mobility by external cues. Genetic studies have identified >100 components that participate in chemotaxis, which hinders the identification of the conceptual framework of how cells sense and respond to shallow chemical gradients. The activation of Ras occurs d...
Autores principales: | van Haastert, Peter J. M., Keizer-Gunnink, Ineke, Kortholt, Arjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385941/ https://www.ncbi.nlm.nih.gov/pubmed/28148648 http://dx.doi.org/10.1091/mbc.E16-10-0733 |
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