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HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex

Rab GTPases, their effectors, SNAREs of the R, Qa, Qb, and Qc families, and SM SNARE-binding proteins catalyze intracellular membrane fusion. At the vacuole/lysosome, they are integrated by the homotypic fusion and vacuole protein sorting (HOPS) complex. Two HOPS subunits bind vacuolar Rabs for teth...

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Detalles Bibliográficos
Autores principales: Orr, Amy, Song, Hongki, Rusin, Scott F., Kettenbach, Arminja N., Wickner, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385945/
https://www.ncbi.nlm.nih.gov/pubmed/28148647
http://dx.doi.org/10.1091/mbc.E16-10-0743

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