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Variable mechanical ventilation

OBJECTIVE: To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique. METHODS: Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electr...

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Autores principales: Fontela, Paula Caitano, Prestes, Renata Bernardy, Forgiarini Jr., Luiz Alberto, Friedman, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385989/
https://www.ncbi.nlm.nih.gov/pubmed/28444076
http://dx.doi.org/10.5935/0103-507X.20170012
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author Fontela, Paula Caitano
Prestes, Renata Bernardy
Forgiarini Jr., Luiz Alberto
Friedman, Gilberto
author_facet Fontela, Paula Caitano
Prestes, Renata Bernardy
Forgiarini Jr., Luiz Alberto
Friedman, Gilberto
author_sort Fontela, Paula Caitano
collection PubMed
description OBJECTIVE: To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique. METHODS: Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electronic databases LILACS, MEDLINE(®), and PubMed, by searching the terms "variable ventilation" OR "noisy ventilation" OR "biologically variable ventilation". RESULTS: A total of 36 studies were selected. Of these, 24 were original studies, including 21 experimental studies and three clinical studies. CONCLUSION: Several experimental studies reported the beneficial effects of distinct variable ventilation strategies on lung function using different models of lung injury and healthy lungs. Variable ventilation seems to be a viable strategy for improving gas exchange and respiratory mechanics and preventing lung injury associated with mechanical ventilation. However, further clinical studies are necessary to assess the potential of variable ventilation strategies for the clinical improvement of patients undergoing mechanical ventilation.
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spelling pubmed-53859892017-04-14 Variable mechanical ventilation Fontela, Paula Caitano Prestes, Renata Bernardy Forgiarini Jr., Luiz Alberto Friedman, Gilberto Rev Bras Ter Intensiva Review Articles OBJECTIVE: To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique. METHODS: Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electronic databases LILACS, MEDLINE(®), and PubMed, by searching the terms "variable ventilation" OR "noisy ventilation" OR "biologically variable ventilation". RESULTS: A total of 36 studies were selected. Of these, 24 were original studies, including 21 experimental studies and three clinical studies. CONCLUSION: Several experimental studies reported the beneficial effects of distinct variable ventilation strategies on lung function using different models of lung injury and healthy lungs. Variable ventilation seems to be a viable strategy for improving gas exchange and respiratory mechanics and preventing lung injury associated with mechanical ventilation. However, further clinical studies are necessary to assess the potential of variable ventilation strategies for the clinical improvement of patients undergoing mechanical ventilation. Associação de Medicina Intensiva Brasileira - AMIB 2017 /pmc/articles/PMC5385989/ /pubmed/28444076 http://dx.doi.org/10.5935/0103-507X.20170012 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Fontela, Paula Caitano
Prestes, Renata Bernardy
Forgiarini Jr., Luiz Alberto
Friedman, Gilberto
Variable mechanical ventilation
title Variable mechanical ventilation
title_full Variable mechanical ventilation
title_fullStr Variable mechanical ventilation
title_full_unstemmed Variable mechanical ventilation
title_short Variable mechanical ventilation
title_sort variable mechanical ventilation
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385989/
https://www.ncbi.nlm.nih.gov/pubmed/28444076
http://dx.doi.org/10.5935/0103-507X.20170012
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