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Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review

Although most patients with takotsubo cardiomyopathy have a favorable outcome, complications are not uncommon. Recent studies have reported an increase in incidence of cardioembolic complications; however, the association between takotsubo cardiomyopathy and stroke, in particular thromboembolic cere...

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Autores principales: Otani, Yoshihiro, Tokunaga, Koji, Kawauchi, Satoshi, Inoue, Satoshi, Watanabe, Kyoichi, Kiriyama, Hideki, Sakane, Kosuke, Maekawa, Kiyoaki, Date, Isao, Matsumoto, Kengo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386162/
https://www.ncbi.nlm.nih.gov/pubmed/28664012
http://dx.doi.org/10.2176/nmccrj.cr.2016-0034
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author Otani, Yoshihiro
Tokunaga, Koji
Kawauchi, Satoshi
Inoue, Satoshi
Watanabe, Kyoichi
Kiriyama, Hideki
Sakane, Kosuke
Maekawa, Kiyoaki
Date, Isao
Matsumoto, Kengo
author_facet Otani, Yoshihiro
Tokunaga, Koji
Kawauchi, Satoshi
Inoue, Satoshi
Watanabe, Kyoichi
Kiriyama, Hideki
Sakane, Kosuke
Maekawa, Kiyoaki
Date, Isao
Matsumoto, Kengo
author_sort Otani, Yoshihiro
collection PubMed
description Although most patients with takotsubo cardiomyopathy have a favorable outcome, complications are not uncommon. Recent studies have reported an increase in incidence of cardioembolic complications; however, the association between takotsubo cardiomyopathy and stroke, in particular thromboembolic cerebral infarction, remains unclear. We reported a 44-year-old woman who had a cerebral infarction resulting from takotsubo cardiomyopathy. She had felt chest discomfort a few days prior to infarction, and later developed left hemiparesis. Head magnetic resonance imaging (MRI) revealed acute infarction in the right insular cortex and occlusion of the right middle cerebral artery at the M2 segment. Echocardiogram revealed a takotsubo-like shape in the motion of the left ventricular wall, and coronary angiography showed neither coronary stenosis nor occlusion. Cerebral infarction resulting from takotsubo cardiomyopathy was diagnosed and treatment with anticoagulant was started. MRI on the eighth day after hospitalization showed recanalization of the right middle cerebral artery and no new ischemic lesions. The findings of the 19 previously published cases who had cerebral infarction resulting from takotsubo cardiomyopathy were also reviewed and showed the median interval between takotsubo cardiomyopathy and cerebral infarction was approximately 1 week and cardiac thrombus was detected in 9 of 19 patients. We revealed that thromboembolic events occurred later than other complications of takotsubo cardiomyopathy and longer observation might be required due to possible cardiogenic cerebral infarction. Anticoagulant therapy is recommended for patients with takotsubo cardiomyopathy with cardiac thrombus or a large area of akinetic left ventricle.
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spelling pubmed-53861622017-06-29 Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review Otani, Yoshihiro Tokunaga, Koji Kawauchi, Satoshi Inoue, Satoshi Watanabe, Kyoichi Kiriyama, Hideki Sakane, Kosuke Maekawa, Kiyoaki Date, Isao Matsumoto, Kengo NMC Case Rep J Case Report Although most patients with takotsubo cardiomyopathy have a favorable outcome, complications are not uncommon. Recent studies have reported an increase in incidence of cardioembolic complications; however, the association between takotsubo cardiomyopathy and stroke, in particular thromboembolic cerebral infarction, remains unclear. We reported a 44-year-old woman who had a cerebral infarction resulting from takotsubo cardiomyopathy. She had felt chest discomfort a few days prior to infarction, and later developed left hemiparesis. Head magnetic resonance imaging (MRI) revealed acute infarction in the right insular cortex and occlusion of the right middle cerebral artery at the M2 segment. Echocardiogram revealed a takotsubo-like shape in the motion of the left ventricular wall, and coronary angiography showed neither coronary stenosis nor occlusion. Cerebral infarction resulting from takotsubo cardiomyopathy was diagnosed and treatment with anticoagulant was started. MRI on the eighth day after hospitalization showed recanalization of the right middle cerebral artery and no new ischemic lesions. The findings of the 19 previously published cases who had cerebral infarction resulting from takotsubo cardiomyopathy were also reviewed and showed the median interval between takotsubo cardiomyopathy and cerebral infarction was approximately 1 week and cardiac thrombus was detected in 9 of 19 patients. We revealed that thromboembolic events occurred later than other complications of takotsubo cardiomyopathy and longer observation might be required due to possible cardiogenic cerebral infarction. Anticoagulant therapy is recommended for patients with takotsubo cardiomyopathy with cardiac thrombus or a large area of akinetic left ventricle. The Japan Neurosurgical Society 2016-09-01 /pmc/articles/PMC5386162/ /pubmed/28664012 http://dx.doi.org/10.2176/nmccrj.cr.2016-0034 Text en Copyright © 2016 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Otani, Yoshihiro
Tokunaga, Koji
Kawauchi, Satoshi
Inoue, Satoshi
Watanabe, Kyoichi
Kiriyama, Hideki
Sakane, Kosuke
Maekawa, Kiyoaki
Date, Isao
Matsumoto, Kengo
Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title_full Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title_fullStr Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title_full_unstemmed Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title_short Cerebral Infarction Arising from Takotsubo Cardiomyopathy: Case Report and Literature Review
title_sort cerebral infarction arising from takotsubo cardiomyopathy: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386162/
https://www.ncbi.nlm.nih.gov/pubmed/28664012
http://dx.doi.org/10.2176/nmccrj.cr.2016-0034
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