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PrP(Sc) formation and clearance as determinants of prion tropism
Prion strains are characterized by strain-specific differences in neuropathology but can also differ in incubation period, clinical disease, host-range and tissue tropism. The hyper (HY) and drowsy (DY) strains of hamster-adapted transmissible mink encephalopathy (TME) differ in tissue tropism and s...
Autores principales: | Shikiya, Ronald A., Langenfeld, Katie A., Eckland, Thomas E., Trinh, Jonathan, Holec, Sara A. M., Mathiason, Candace K., Kincaid, Anthony E., Bartz, Jason C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386299/ https://www.ncbi.nlm.nih.gov/pubmed/28355274 http://dx.doi.org/10.1371/journal.ppat.1006298 |
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