Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy

Noonan syndrome (NS) is characterized by reduced growth, craniofacial abnormalities, congenital heart defects, and variable cognitive deficits. NS belongs to the RASopathies, genetic conditions linked to mutations in components and regulators of the Ras signaling pathway. Approximately 50% of NS cas...

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Detalles Bibliográficos
Autores principales: Altmüller, Franziska, Pothula, Santosh, Annamneedi, Anil, Nakhaei-Rad, Saeideh, Montenegro-Venegas, Carolina, Pina-Fernández, Eneko, Marini, Claudia, Santos, Monica, Schanze, Denny, Montag, Dirk, Ahmadian, Mohammad R., Stork, Oliver, Zenker, Martin, Fejtova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386306/
https://www.ncbi.nlm.nih.gov/pubmed/28346493
http://dx.doi.org/10.1371/journal.pgen.1006684

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