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Identification of a genetically defined ultra-high-risk group in relapsed pediatric T-lymphoblastic leukemia
In the search for genes that define critical steps of relapse in pediatric T-cell acute lymphoblastic leukemia (T-ALL) and can serve as prognostic markers, we performed targeted sequencing of 313 leukemia-related genes in 214 patients: 67 samples collected at the time of relapse and 147 at initial d...
Autores principales: | Richter-Pechańska, P, Kunz, J B, Hof, J, Zimmermann, M, Rausch, T, Bandapalli, O R, Orlova, E, Scapinello, G, Sagi, J C, Stanulla, M, Schrappe, M, Cario, G, Kirschner-Schwabe, R, Eckert, C, Benes, V, Korbel, J O, Muckenthaler, M U, Kulozik, A E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386337/ https://www.ncbi.nlm.nih.gov/pubmed/28157215 http://dx.doi.org/10.1038/bcj.2017.3 |
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