Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation

Cystic fibrosis (CF), the most common lethal monogenic disease in Caucasians, is characterized by recurrent bacterial infections and colonization, mainly by Pseudomonas aeruginosa, resulting in unresolved airway inflammation. CF is caused by mutations in the gene coding for the cystic fibrosis trans...

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Detalles Bibliográficos
Autores principales: Ferrari, Eleonora, Monzani, Romina, Villella, Valeria R, Esposito, Speranza, Saluzzo, Francesca, Rossin, Federica, D'Eletto, Manuela, Tosco, Antonella, De Gregorio, Fabiola, Izzo, Valentina, Maiuri, Maria C, Kroemer, Guido, Raia, Valeria, Maiuri, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386380/
https://www.ncbi.nlm.nih.gov/pubmed/28079883
http://dx.doi.org/10.1038/cddis.2016.476

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