Tsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response

Dendritic cells (DCs) are pivotal to the induction of adaptive T-cell immune responses. Recent evidence highlights a critical role of tuberous sclerosis complex 1 (Tsc1), a primarily upstream negative regulator of mammalian target of rapamycin (mTOR), in DC development, but whether and how Tsc1 dire...

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Detalles Bibliográficos
Autores principales: Luo, Yuechen, Li, Wenwen, Yu, Gang, Yu, Juan, Han, Ling, Xue, Ting, Sun, Zhina, Chen, Song, Fang, Chunming, Zhao, Chunxiao, Niu, Qing, Yang, Fei, Han, Zhongchao, Cheng, Tao, Zeng, Yun, Liao, Fang, Xu, Guogang, Feng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386387/
https://www.ncbi.nlm.nih.gov/pubmed/28079897
http://dx.doi.org/10.1038/cddis.2016.487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386387/
https://www.ncbi.nlm.nih.gov/pubmed/28079897
http://dx.doi.org/10.1038/cddis.2016.487

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