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Foot-and-mouth disease virus infection suppresses autophagy and NF-кB antiviral responses via degradation of ATG5-ATG12 by 3C(pro)

Autophagy-related protein ATG5-ATG12 is an essential complex for the autophagophore elongation in autophagy, which has been reported to be involved in foot-and-mouth disease virus (FMDV) replication. Previous reports show that ATG5-ATG12 positively or negatively regulates type I interferon (IFN-α/β)...

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Detalles Bibliográficos
Autores principales:	Fan, Xuxu, Han, Shichong, Yan, Dan, Gao, Yuan, Wei, Yanquan, Liu, Xiangtao, Liao, Ying, Guo, Huichen, Sun, Shiqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386389/ https://www.ncbi.nlm.nih.gov/pubmed/28102839 http://dx.doi.org/10.1038/cddis.2016.489

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