NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages

A limit to the clinical benefit of radiotherapy is not an incapacity to eliminate tumor cells but rather a limit on its capacity to do so without destroying normal tissue and inducing inflammation. Recent evidence reveals that the inflammasome is essential for mediating radiation-induced cell and ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yan-gang, Chen, Ji-kuai, Zhang, Zi-teng, Ma, Xiu-juan, Chen, Yong-chun, Du, Xiu-ming, Liu, Hong, Zong, Ying, Lu, Guo-cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386456/
https://www.ncbi.nlm.nih.gov/pubmed/28151471
http://dx.doi.org/10.1038/cddis.2016.460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386456/
https://www.ncbi.nlm.nih.gov/pubmed/28151471
http://dx.doi.org/10.1038/cddis.2016.460

Ejemplares similares