Knockout of Eva1a leads to rapid development of heart failure by impairing autophagy

EVA1A (Eva-1 homologue A) is a novel lysosome and endoplasmic reticulum-associated protein that can regulate cell autophagy and apoptosis. Eva1a is expressed in the myocardium, but its function in myocytes has not yet been investigated. Therefore, we generated inducible, cardiomyocyte-specific Eva1a...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Lin, Xin, Li, Ge, Shen, Xue, Niu, Di, Lu, Guang, Fu, Xin, Chen, Yingyu, Cui, Ming, Bai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386466/
https://www.ncbi.nlm.nih.gov/pubmed/28151473
http://dx.doi.org/10.1038/cddis.2017.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386466/
https://www.ncbi.nlm.nih.gov/pubmed/28151473
http://dx.doi.org/10.1038/cddis.2017.17

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