Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway

Brahma-related gene-1 (BRG1) is the specific ATPase of switch/sucrose nonfermentable chromatin-remodeling complex that is aberrantly expressed or mutated in various cancers. However, the exact role of BRG1 in oncogenesis remains unknown. In this study, we demonstrate that the knockdown (KD) of BRG1...

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Detalles Bibliográficos
Autores principales: Wang, Guihua, Fu, Yinjia, Hu, Fuqing, Lan, Jinqing, Xu, Feng, Yang, Xi, Luo, Xuelai, Wang, Jing, Hu, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386468/
https://www.ncbi.nlm.nih.gov/pubmed/28182012
http://dx.doi.org/10.1038/cddis.2017.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386468/
https://www.ncbi.nlm.nih.gov/pubmed/28182012
http://dx.doi.org/10.1038/cddis.2017.1

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