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Tenovin-6 impairs autophagy by inhibiting autophagic flux

Tenovin-6 has attracted significant interest because it activates p53 and inhibits sirtuins. It has anti-neoplastic effects on multiple hematopoietic malignancies and solid tumors in both in vitro and in vivo studies. Tenovin-6 was recently shown to impair the autophagy pathway in chronic lymphocyti...

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Detalles Bibliográficos
Autores principales:	Yuan, Hongfeng, Tan, Brandon, Gao, Shou-Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386474/ https://www.ncbi.nlm.nih.gov/pubmed/28182004 http://dx.doi.org/10.1038/cddis.2017.25

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