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Starvation at birth impairs germ cell cyst breakdown and increases autophagy and apoptosis in mouse oocytes

The female reproductive lifespan is largely determined by the size of primordial follicle pool, which is established following germ cell cyst breakdown around birth. Almost two-third of oocytes are lost during germ cell cysts breakdown, following autophagic and apoptosis mechanisms. To investigate a...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Yong, Sun, Yuan-Chao, Sun, Xiao-Feng, Cheng, Shun-Feng, Li, Bo, Zhang, Xi-Feng, De Felici, Massimo, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386484/
https://www.ncbi.nlm.nih.gov/pubmed/28182014
http://dx.doi.org/10.1038/cddis.2017.3