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Starvation at birth impairs germ cell cyst breakdown and increases autophagy and apoptosis in mouse oocytes
The female reproductive lifespan is largely determined by the size of primordial follicle pool, which is established following germ cell cyst breakdown around birth. Almost two-third of oocytes are lost during germ cell cysts breakdown, following autophagic and apoptosis mechanisms. To investigate a...
Autores principales: | Wang, Yong-Yong, Sun, Yuan-Chao, Sun, Xiao-Feng, Cheng, Shun-Feng, Li, Bo, Zhang, Xi-Feng, De Felici, Massimo, Shen, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386484/ https://www.ncbi.nlm.nih.gov/pubmed/28182014 http://dx.doi.org/10.1038/cddis.2017.3 |
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