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Mesenchymal stromal cells inhibit CD25 expression via the mTOR pathway to potentiate T-cell suppression
Mesenchymal stromal cells (MSCs) are known to suppress T-cell activation and proliferation. Several studies have reported that MSCs suppress CD25 expression in T cells. However, the molecular mechanism underlying MSC-mediated suppression of CD25 expression has not been fully examined. Here, we inves...
Autores principales: | Yoo, Hyun Seung, Lee, Kyuheon, Na, Kwangmin, Zhang, Yong Xu, Lim, Hyun-Ja, Yi, TacGhee, Song, Sun U, Jeon, Myung-Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386489/ https://www.ncbi.nlm.nih.gov/pubmed/28230853 http://dx.doi.org/10.1038/cddis.2017.45 |
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