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Thioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression

Carboplatin is a less toxic analog of cisplatin, but carboplatin also has side effects, including bone marrow suppression. Therefore, to improve the capacity of the anticancer activity of carboplatin, we investigated whether combined treatment with carboplatin and thioridazine, which has antipsychot...

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Detalles Bibliográficos
Autores principales:	Seo, Seung Un, Cho, Hyuk Ki, Min, Kyoung-jin, Woo, Seon Min, Kim, Shin, Park, Jong-Wook, Kim, Sang Hyun, Choi, Yung Hyun, Keum, Young Sam, Hyun, Jin Won, Park, Hyun Ho, Lee, Sang-Han, Kim, Dong Eun, Kwon, Taeg Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386499/ https://www.ncbi.nlm.nih.gov/pubmed/28182008 http://dx.doi.org/10.1038/cddis.2017.8

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