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Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
Cystatin SN (CST1) is a specific inhibitor belonging to the cystatin superfamily that controls the proteolytic activities of cysteine proteases such as cathepsins. Our previous study showed that high CST1 expression enhances tumor metastasis and invasiveness in colorectal cancer. Recently, auranofin...
Autores principales: | Oh, Byung Moo, Lee, Seon-Jin, Cho, Hee Jun, Park, Yun Sun, Kim, Jong-Tae, Yoon, Suk Ran, Lee, Sang Chul, Lim, Jong-Seok, Kim, Bo-Yeon, Choe, Yong-Kyung, Lee, Hee Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386512/ https://www.ncbi.nlm.nih.gov/pubmed/28300829 http://dx.doi.org/10.1038/cddis.2017.100 |
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