Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer

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Cystatin SN (CST1) is a specific inhibitor belonging to the cystatin superfamily that controls the proteolytic activities of cysteine proteases such as cathepsins. Our previous study showed that high CST1 expression enhances tumor metastasis and invasiveness in colorectal cancer. Recently, auranofin...

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Detalles Bibliográficos
Autores principales: Oh, Byung Moo, Lee, Seon-Jin, Cho, Hee Jun, Park, Yun Sun, Kim, Jong-Tae, Yoon, Suk Ran, Lee, Sang Chul, Lim, Jong-Seok, Kim, Bo-Yeon, Choe, Yong-Kyung, Lee, Hee Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386512/
https://www.ncbi.nlm.nih.gov/pubmed/28300829
http://dx.doi.org/10.1038/cddis.2017.100
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