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FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis

Global germ line loss of fat mass- and obesity-associated (FTO) gene results in both the reduction of fat mass and lean mass in mice. The role of FTO in adipogenesis has been proposed, however, that in myogenesis has not. Skeletal muscle is the main component of body lean mass, so its connection wit...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaobo, Huang, Ning, Yang, Min, Wei, Dandan, Tai, Haoran, Han, Xiaojuan, Gong, Hui, Zhou, Jiao, Qin, Jianqiong, Wei, Xiawei, Chen, Honghan, Fang, Tingting, Xiao, Hengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386528/ https://www.ncbi.nlm.nih.gov/pubmed/28333151 http://dx.doi.org/10.1038/cddis.2017.122

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