Hydrogen sulfide promotes autophagy of hepatocellular carcinoma cells through the PI3K/Akt/mTOR signaling pathway

Hydrogen sulfide (H(2)S), in its gaseous form, plays an important role in tumor carcinogenesis. This study investigated the effects of H(2)S on the cell biological functions of hepatocellular carcinoma (HCC). HCC cell lines, HepG2 and HLE, were treated with NaHS, a donor of H(2)S, and rapamycin, a c...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan S, Chen, Yuhan H, Chen, Ning, Wang, Lijun J, Chen, Dexi X, Weng, Honglei L, Dooley, Steven, Ding, Huiguo G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386547/
https://www.ncbi.nlm.nih.gov/pubmed/28333142
http://dx.doi.org/10.1038/cddis.2017.18

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