Nuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 and CD82 in gastric cancer

Drosha is an RNA III-like enzyme that has an aberrant expression in some tumors. Our previous studies showed the aberrant Drosha in gastric tumors. However, the roles of nuclear Drosha, the main regulator of microRNA (miRNA) biogenesis, in gastric cancer (GC) progression remain poorly understood. In...

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Detalles Bibliográficos
Autores principales: Xu, Liyun, Hou, Yixuan, Tu, Gang, Chen, Yanlin, Du, Yan-e, Zhang, Hailong, Wen, Siyang, Tang, Xi, Yin, Jiali, Lang, Lei, Sun, Kexin, Yang, Guanglun, Tang, Xiaoli, Liu, Manran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386557/
https://www.ncbi.nlm.nih.gov/pubmed/28252644
http://dx.doi.org/10.1038/cddis.2017.5

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