Endogenous AMPK acts as a detrimental factor in fulminant hepatitis via potentiating JNK-dependent hepatocyte apoptosis

The energy sensor AMP-activated protein kinase (AMPK) is crucial for energy homeostasis. Recent studies have revealed that AMPK is involved in various energy-intensive pathological processes such as inflammation and apoptosis. The physiological functions of hepatic AMPK have been well studied, but t...

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Detalles Bibliográficos
Autores principales: Hu, Kai, Gong, Xianqiong, Ai, Qing, Lin, Ling, Dai, Jie, Cai, Lu, Jiang, Rong, Ge, Pu, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386558/
https://www.ncbi.nlm.nih.gov/pubmed/28252653
http://dx.doi.org/10.1038/cddis.2017.62

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