BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis

Following inhalation into the lungs, silica particles are engulfed by alveolar macrophages, which triggers endogenous or exogenous apoptosis signaling pathways. As an inducer of apoptosis, the role of BBC3/PUMA (BCL2-binding component 3) in macrophages during silicosis remains unknown. Here, we expo...

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Detalles Bibliográficos
Autores principales: Liu, Haijun, Cheng, Yusi, Yang, Jian, Wang, Wei, Fang, Shencun, Zhang, Wei, Han, Bing, Zhou, Zewei, Yao, Honghong, Chao, Jie, Liao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386570/
https://www.ncbi.nlm.nih.gov/pubmed/28277537
http://dx.doi.org/10.1038/cddis.2017.78

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