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IL-27 triggers IL-10 production in Th17 cells via a c-Maf/RORγt/Blimp-1 signal to promote the progression of endometriosis

Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. However, the mechanism of inducing IL-10-producing Th17 cells is stil...

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Detalles Bibliográficos
Autores principales: Chang, Kai-Kai, Liu, Li-Bing, Jin, Li-Ping, Zhang, Bing, Mei, Jie, Li, Hui, Wei, Chun-Yan, Zhou, Wen-Jie, Zhu, Xiao-Yong, Shao, Jun, Li, Da-Jin, Li, Ming-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386585/
https://www.ncbi.nlm.nih.gov/pubmed/28300844
http://dx.doi.org/10.1038/cddis.2017.95

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