Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

The spatiotemporal transmission of pathological tau in the brain is characteristic of Alzheimer's disease. Release of both soluble and abnormal tau species from healthy neurons is increased upon stimulation of neuronal activity. It is not yet understood whether the mechanisms controlling solubl...

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Detalles Bibliográficos
Autores principales: Croft, Cara L, Wade, Matthew A, Kurbatskaya, Ksenia, Mastrandreas, Pavlina, Hughes, Martina M, Phillips, Emma C, Pooler, Amy M, Perkinton, Michael S, Hanger, Diane P, Noble, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386587/
https://www.ncbi.nlm.nih.gov/pubmed/28300838
http://dx.doi.org/10.1038/cddis.2017.97

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