Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor-γ (PPARγ) are disrupted by retinal disease-associated mutations

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the nuclear receptor (NR) superfamily of transcription factors. We assessed the ability of these NRs to form heterodimers with...

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Detalles Bibliográficos
Autores principales: Fulton, Joel, Mazumder, Bismoy, Whitchurch, Jonathan B, Monteiro, Cintia J, Collins, Hilary M, Chan, Chun M, Clemente, Maria P, Hernandez-Quiles, Miguel, Stewart, Elizabeth A, Amoaku, Winfried M, Moran, Paula M, Mongan, Nigel P, Persson, Jenny L, Ali, Simak, Heery, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386588/
https://www.ncbi.nlm.nih.gov/pubmed/28300834
http://dx.doi.org/10.1038/cddis.2017.98

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