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Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization
Intra-tumor heterogeneity is a pervasive property of human cancers that poses a major clinical challenge. Here, we describe the characterization, at the transcriptional level, of the intra-tumor topography of two prominent breast cancer biomarkers and drug targets, epidermal growth factor receptor 2...
Autores principales: | Annaratone, Laura, Simonetti, Michele, Wernersson, Erik, Marchiò, Caterina, Garnerone, Silvano, Scalzo, Maria Stella, Bienko, Magda, Chiarle, Roberto, Sapino, Anna, Crosetto, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386639/ https://www.ncbi.nlm.nih.gov/pubmed/28423635 http://dx.doi.org/10.18632/oncotarget.15727 |
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