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Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma

MET is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and degraded by c-CBL E3-ubiquitin ligase. We investigated genetic variations of c-CBL in HNSCC and the relationship between c-CBL and MET expression. High MET, low c-CBL expression was detected in 10 cell lines and 73...

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Detalles Bibliográficos
Autores principales:	Rolle, Cleo E., Tan, Yi-Hung Carol, Seiwert, Tanguy Y., Vora, Sapana, Kanteti, Rajani, Hasina, Rifat, Carey, George B., Surati, Mosmi, Weichselbaum, Ralph R., Lingen, Mark W., Vokes, Everett E., Salgia, Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386642/ https://www.ncbi.nlm.nih.gov/pubmed/27244893 http://dx.doi.org/10.18632/oncotarget.9640

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