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Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer
E-cadherin is a cell-cell adhesion protein encoded by CDH1 tumor-suppressor gene. CDH1 inactivating mutations, leading to loss of protein expression, are common in gastric cancer of the diffuse histotype, while alternative mechanisms modulating E-cadherin expression characterize the more common inte...
Autores principales: | Khouzam, Raefa Abou, Molinari, Chiara, Salvi, Samanta, Marabelli, Monica, Molinaro, Valeria, Orioli, Donata, Saragoni, Luca, Morgagni, Paolo, Calistri, Daniele, Ranzani, Guglielmina Nadia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386649/ https://www.ncbi.nlm.nih.gov/pubmed/27861150 http://dx.doi.org/10.18632/oncotarget.13401 |
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