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Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice

Previous Epstein-Barr virus (EBV) prophylactic vaccines based on the major surface glycoprotein gp350/220 as an immunogen have failed to block viral infection in humans, suggesting a need to target other viral envelope glycoproteins. In this study, we reasoned that incorporating gH/gL or gB, critica...

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Detalles Bibliográficos
Autores principales:	Perez, Elizabeth M., Foley, Joslyn, Tison, Timelia, Silva, Rute, Ogembo, Javier Gordon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386682/ https://www.ncbi.nlm.nih.gov/pubmed/27926486 http://dx.doi.org/10.18632/oncotarget.13770

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