Cargando…

Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein

The function of a conserved PDS95/DLG1/ZO1 (PDZ) binding motif (E6 PBM) at the C-termini of E6 oncoproteins of high-risk human papillomavirus (HPV) types contributes to the development of HPV-associated malignancies. Here, using a primary human keratinocyte-based model of the high-risk HPV18 life cy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marsh, Elizabeth K., Delury, Craig P., Davies, Nicholas J., Weston, Christopher J., Miah, Mohammed A.L., Banks, Lawrence, Parish, Joanna L., Higgs, Martin R, Roberts, Sally
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386700/ https://www.ncbi.nlm.nih.gov/pubmed/28061478 http://dx.doi.org/10.18632/oncotarget.14469

Ejemplares similares

The Role of Protein Kinase A Regulation of the E6 PDZ-Binding Domain during the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 18
por: Delury, Craig P., et al.
Publicado: (2013)

The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy
por: Ganti, Ketaki, et al.
Publicado: (2015)

An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
por: Belyaeva, Tamara A., et al.
Publicado: (2014)

The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
por: Cortés-Malagón, Enoc Mariano, et al.
Publicado: (2017)

Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses
por: Ainsworth, Julia, et al.
Publicado: (2008)

Viral Interactions with PDZ Domain-Containing Proteins—An Oncogenic Trait?
por: James, Claire D., et al.
Publicado: (2016)

Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein
por: Genera, Mariano, et al.
Publicado: (2019)

Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways
por: Ganti, Ketaki, et al.
Publicado: (2016)

Human papillomavirus oncoproteins and apoptosis (Review)
por: JIANG, PEIYUE, et al.
Publicado: (2014)

Structural Insights in Multifunctional Papillomavirus Oncoproteins
por: Suarez, Irina, et al.
Publicado: (2018)

Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential
por: Thomas, Miranda, et al.
Publicado: (2016)

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line
por: Tsubata, Chikako, et al.
Publicado: (2005)

Inhibition of kinase IKKβ suppresses cellular abnormalities induced by the human papillomavirus oncoprotein HPV 18E6
por: Padash Barmchi, Mojgan, et al.
Publicado: (2021)

Structural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ Domain
por: Mischo, André, et al.
Publicado: (2013)

Golgi Alkalinization by the Papillomavirus E5 Oncoprotein
por: Schapiro, Florencia, et al.
Publicado: (2000)

Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif
por: Nagashima, Shunta, et al.
Publicado: (2016)

Modelling human papillomavirus biology in oropharyngeal keratinocytes
por: Roberts, Sally, et al.
Publicado: (2019)

Epigenetic regulation of human papillomavirus transcription in the productive virus life cycle
por: Burley, Megan, et al.
Publicado: (2020)

Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma
por: Yang, Liqun, et al.
Publicado: (2017)

Papillomavirus E5: the smallest oncoprotein with many functions
por: Venuti, Aldo, et al.
Publicado: (2011)

Subversion of Host Innate Immunity by Human Papillomavirus Oncoproteins
por: Lo Cigno, Irene, et al.
Publicado: (2020)

PDZ-Containing Proteins Targeted by the ACE2 Receptor
por: Caillet-Saguy, Célia, et al.
Publicado: (2021)

Zasp: A New Z-Band Alternatively Spliced PDZ-Motif Protein
por: Faulkner, Georgine, et al.
Publicado: (1999)

Prediction and Experimental Characterization of nsSNPs Altering Human PDZ-Binding Motifs
por: Gfeller, David, et al.
Publicado: (2014)

Transcriptional coactivator with PDZ‐binding motif is required to sustain testicular function on aging
por: Jeong, Mi Gyeong, et al.
Publicado: (2017)

Yes-Associated Protein and Transcriptional Coactivator with PDZ-Binding Motif in Cardiovascular Diseases
por: Li, Ruojun, et al.
Publicado: (2023)

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in Monosiga brevicollis PDZ Domains Using Human PDZ Data
por: Wofford, Haley A., et al.
Publicado: (2021)

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6
por: Ye, Xiyun, et al.
Publicado: (2023)

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins
por: Thomas, Miranda, et al.
Publicado: (2011)

Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development
por: Rozengurt, Enrique, et al.
Publicado: (2019)

The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins
por: Maksimchuk, Kenneth R., et al.
Publicado: (2016)

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
por: Scarth, James A., et al.
Publicado: (2021)

Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif
por: Chimura, Takahiko, et al.
Publicado: (2011)

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs
por: Ali, Muhammad, et al.
Publicado: (2021)

Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels
por: Chai, Zhifang, et al.
Publicado: (2011)

An interaction map for HTLV-1 Tax and PDZ-containing proteins
por: Blibek, Karim, et al.
Publicado: (2014)

Correlation between the coexpression of zinc finger and SCAN domain-containing protein 31 and transcriptional activator with PDZ-binding motif and prognosis in hepatocellular carcinoma
por: Liu, Qiang, et al.
Publicado: (2020)

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
por: Zhao, Jiawei, et al.
Publicado: (2019)

Targeting Human Papillomavirus-Associated Cancer by Oncoprotein-Specific Recombinant Antibodies
por: Donà, Maria Gabriella, et al.
Publicado: (2021)

The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis
por: Jimenez-Guardeño, Jose M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_i8sgdit2d6p0rhrqoi1asncng8