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CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle

Heterochromatin protein 1γ (CBX3) links histone methylation marks to transcriptional silence, DNA repair and RNA splicing, but a role for CBX3 in cancer remains largely unknown. In this study, we show that CBX3 in colon cancer cells promotes the progression of the cell cycle and proliferation in vit...

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Detalles Bibliográficos
Autores principales: Fan, Yao, Li, Haiping, Liang, Xiaolong, Xiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386735/
https://www.ncbi.nlm.nih.gov/pubmed/28193906
http://dx.doi.org/10.18632/oncotarget.15253