The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes

The PI3K/PTEN/AKT pathway play a critical role in balancing cell growth and death. Epidemiologic studies suggested that mutations of the PI3K/PTEN/AKT pathway genes are associated with cancer risk, yet no data are available for PTEN rs701848, PIK3CA rs2699887, and AKT1 rs2494752 polymorphism and bre...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiang, Zhang, Ruishan, Liu, Zhuangkai, Li, Shuang, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386760/
https://www.ncbi.nlm.nih.gov/pubmed/28423632
http://dx.doi.org/10.18632/oncotarget.15690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386760/
https://www.ncbi.nlm.nih.gov/pubmed/28423632
http://dx.doi.org/10.18632/oncotarget.15690

Ejemplares similares