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The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes

The PI3K/PTEN/AKT pathway play a critical role in balancing cell growth and death. Epidemiologic studies suggested that mutations of the PI3K/PTEN/AKT pathway genes are associated with cancer risk, yet no data are available for PTEN rs701848, PIK3CA rs2699887, and AKT1 rs2494752 polymorphism and bre...

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Detalles Bibliográficos
Autores principales:	Li, Xiang, Zhang, Ruishan, Liu, Zhuangkai, Li, Shuang, Xu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386760/ https://www.ncbi.nlm.nih.gov/pubmed/28423632 http://dx.doi.org/10.18632/oncotarget.15690

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