The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer

AIM: To determine the regulation and function of the neural precursor cell expressed developmentally down regulated protein 4 (NEDD4) in PDAC and to determine its dependency on phosphatase and tensin homolog (PTEN) and PI3K/AKT signaling. METHODS: We investigated the expression of NEDD4 and the tumo...

Descripción completa

Detalles Bibliográficos
Autores principales: Weng, Min, Luo, Zhu-Lin, Wu, Xiao-Ling, Zeng, Wei-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386762/
https://www.ncbi.nlm.nih.gov/pubmed/28423617
http://dx.doi.org/10.18632/oncotarget.15446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386762/
https://www.ncbi.nlm.nih.gov/pubmed/28423617
http://dx.doi.org/10.18632/oncotarget.15446

Ejemplares similares