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Variants of the Sir4 Coiled-Coil Domain Improve Binding to Sir3 for Heterochromatin Formation in Saccharomyces cerevisiae

Heterochromatin formation in the yeast Saccharomyces cerevisiae is characterized by the assembly of the Silent Information Regulator (SIR) complex, which consists of the histone deacetylase Sir2 and the structural components Sir3 and Sir4, and binds to unmodified nucleosomes to provide gene silencin...

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Detalles Bibliográficos
Autores principales:	Samel, Anke, Rudner, Adam, Ehrenhofer-Murray, Ann E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386860/ https://www.ncbi.nlm.nih.gov/pubmed/28188183 http://dx.doi.org/10.1534/g3.116.037739

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