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MYC and AMPK–Save Energy or Die!

MYC sustains non-stop proliferation by altering metabolic machinery to support growth of cell mass. As part of the metabolic transformation MYC promotes lipid, nucleotide and protein synthesis by hijacking citric acid cycle to serve biosynthetic processes, which simultaneously exhausts ATP productio...

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Detalles Bibliográficos
Autores principales: Haikala, Heidi M., Anttila, Johanna M., Klefström, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386972/
https://www.ncbi.nlm.nih.gov/pubmed/28443281
http://dx.doi.org/10.3389/fcell.2017.00038