Dapagliflozin‐lowered blood glucose reduces respiratory Pseudomonas aeruginosa infection in diabetic mice

BACKGROUND AND PURPOSE: Hyperglycaemia increases glucose concentrations in airway surface liquid and increases the risk of pulmonary Pseudomonas aeruginosa infection. We determined whether reduction of blood and airway glucose concentrations by the anti‐diabetic drug dapagliflozin could reduce P. ae...

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Detalles Bibliográficos
Autores principales: Åstrand, Annika, Wingren, Cecilia, Benjamin, Audra, Tregoning, John S, Garnett, James P, Groves, Helen, Gill, Simren, Orogo‐Wenn, Maria, Lundqvist, Anders J, Walters, Dafydd, Smith, David M, Taylor, John D, Baker, Emma H, Baines, Deborah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386993/
https://www.ncbi.nlm.nih.gov/pubmed/28192604
http://dx.doi.org/10.1111/bph.13741

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