Cargando…
Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions
Short Tandem Repeats (STRs) are frequent entities in many transcripts, however, in some cases, pathological events occur when a critical repeat length is reached. This phenomenon is observed in various neurological disorders, such as myotonic dystrophy type 1 (DM1), fragile X-associated tremor/ataxi...
Autores principales: | Ciesiolka, Adam, Jazurek, Magdalena, Drazkowska, Karolina, Krzyzosiak, Wlodzimierz J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387085/ https://www.ncbi.nlm.nih.gov/pubmed/28442996 http://dx.doi.org/10.3389/fncel.2017.00097 |
Ejemplares similares
-
Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases
por: Jazurek, Magdalena, et al.
Publicado: (2016) -
RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders
por: Wojciechowska, Marzena, et al.
Publicado: (2014) -
Reduction of Huntington’s Disease RNA Foci by CAG Repeat-Targeting Reagents
por: Urbanek, Martyna O., et al.
Publicado: (2017) -
A potential role of extended simple sequence repeats in competing endogenous RNA crosstalk
por: Witkos, Tomasz M., et al.
Publicado: (2018) -
Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases
por: Kiliszek, Agnieszka, et al.
Publicado: (2010)