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Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells

The recruitment of bone marrow (BM)‐derived progenitor cells to the lung is related to pulmonary remodelling and the pathogenesis of pulmonary hypertension (PH). Although sildenafil is a known target in PH treatment, the underlying molecular mechanism is still elusive. To test the hypothesis that th...

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Detalles Bibliográficos
Autores principales: Favre, Shirley, Gambini, Elisa, Nigro, Patrizia, Scopece, Alessandro, Bianciardi, Paola, Caretti, Anna, Pompilio, Giulio, Corno, Antonio F., Vassalli, Giuseppe, von Segesser, Ludwig K., Samaja, Michele, Milano, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387166/
https://www.ncbi.nlm.nih.gov/pubmed/27860185
http://dx.doi.org/10.1111/jcmm.13026

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