Effects of miR‐145‐5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways

We aimed to detect the effects of miR‐145‐5p on the cell proliferation, apoptosis, migration, and invasion in NRAS‐mutant, BRAF‐mutant, and wild‐type melanoma cells, in order to figure out the potential mechanisms and provide a novel therapeutic target of melanoma. RT‐qPCR and western blot were used...

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Detalles Bibliográficos
Autores principales: Liu, Sha, Gao, Guozhen, Yan, Dexiong, Chen, Xiangjun, Yao, Xingwei, Guo, Shuzhong, Li, Guirong, Zhao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387172/
https://www.ncbi.nlm.nih.gov/pubmed/28332309
http://dx.doi.org/10.1002/cam4.1030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387172/
https://www.ncbi.nlm.nih.gov/pubmed/28332309
http://dx.doi.org/10.1002/cam4.1030

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